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Adult and Old Lymphocytes
Filesbcells_old_spleen_m5

bcells_old_spleen_m4

bcells_old_spleen_m2

bcells_old_spleen_m1

bcells_old_dln_m1

bcells_old_dln_m4

bcells_old_dln_m3

bcells_old_dln_m2

bcells_adult_spleen_m1

bcells_adult_spleen_m2

bcells_adult_spleen_m4

bcells_adult_spleen_m5

bcells_adult_dln_m1

bcells_adult_dln_m2

bcells_adult_dln_m3

bcells_adult_dln_m4

tcells_adult_dln_m1

tcells_adult_dln_m2

tcells_adult_dln_m3

tcells_adult_ndln_m1

tcells_adult_ndln_m2

tcells_adult_ndln_m3

tcells_old_dln_m1

tcells_old_dln_m2

tcells_old_dln_m3

tcells_old_ndln_m1

tcells_old_ndln_m2

tcells_old_ndln_m3

URLdx.doi.org/10.1371/journal.ppat.1005027
CreatorMark Miller
Uploaded2015-12-15
DescriptionDye-labelled Naive T and B Cells were adoptively transferred from healthy old (18m) or adult (4m) mice into recipient mice infected with West Nile Virus 48 hours earlier. Cells were imaged in draining lymph nodes (dln), non-draining lymph nodes (ndln), and spleen.
ReferenceRichner JM, Gmyrek GB, Govero J, Tu Y, van der Windt GJW, Metcalf TU, et al. (2015) Age-Dependent Cell Trafficking Defects in Draining Lymph Nodes Impair Adaptive Immunity and Control of West Nile Virus Infection. PLoS Pathog 11(7): e1005027.
DOI10.1371/journal.ppat.1005027